Rejuran Alternatives in Korea: Top Skin Regeneration & Collagen-Boosting Options

Rejuran is one of the most recognized skin booster injections in Korea, known for improving skin texture, elasticity, and overall skin health through polynucleotide (PN/PDRN) regeneration. However, Rejuran is not the only option. Korean dermatology clinics frequently recommend alternative injectables based on skin concerns, recovery time, and desired results.

Below is a clear overview of the most popular Rejuran alternatives in Korea, and how each differs in function and outcome.

Juvelook (Collagen-Stimulating Hybrid Injection)

Best for: Skin elasticity, pores, and fine lines
Type: PDLLA + hyaluronic acid

Juvelook is one of the most commonly chosen alternatives to Rejuran in Korea. Rather than focusing on skin repair alone, it stimulates long-term collagen production, making it suitable for patients looking for gradual firming and smoother skin texture.

Why it’s chosen

• Improves elasticity and pores
• Longer-lasting collagen stimulation
• Less post-injection redness than Rejuran for many patients

PN / PDRN Skin Boosters (Non-Rejuran Brands)

Best for: Skin healing, sensitivity, and recovery
Type: Polynucleotide / polydeoxyribonucleotide

Many clinics offer PN or PDRN injections that are not branded as Rejuran. These products work similarly by supporting skin repair, reducing inflammation, and improving barrier function.

Why clinics recommend them

• Gentler option for sensitive skin
• Often used after lasers or procedures
• Similar regenerative benefits with different formulations

Skinvive (Hyaluronic Acid Skin Booster)

Best for: Hydration and fine texture improvement
Type: Microdroplet hyaluronic acid

Skinvive focuses on deep hydration and skin smoothness rather than regeneration. It is commonly recommended to patients who want brighter, smoother skin without downtime or post-treatment sensitivity.

Key differences from Rejuran

• No collagen regeneration
• Immediate hydration-based glow
• Minimal recovery time

Profhilo-Style Bio-Remodeling Injections

Best for: Skin laxity and elasticity
Type: High-concentration hyaluronic acid

Bio-remodeling injectables improve skin firmness by stimulating collagen and elastin indirectly while deeply hydrating the skin. These treatments are often suggested when patients want a balance between skin quality improvement and subtle firming.

Why it’s used as an alternative

• Improves elasticity and firmness
• Spreads evenly under the skin
• Fewer injection points than Rejuran

Sculptra-Type Collagen Stimulators

Best for: Long-term skin density and volume support
Type: PLLA collagen stimulator

For patients focused on structural skin improvement, collagen stimulators are sometimes recommended instead of Rejuran. These injections work over months to thicken the dermis and improve firmness.

How it differs

• Slower onset of results
• Longer-lasting collagen effects
• Not suitable for very thin or sensitive skin without careful planning

Radiesse-Style Biostimulators

Best for: Firmness and skin density
Type: Calcium-based collagen stimulator

When diluted and used for skin quality rather than contouring, biostimulators are sometimes chosen for patients who want firmer skin texture rather than hydration or healing.

Key distinction

• Focuses on firmness, not repair
• Requires experienced technique
• Not a direct regenerative substitute for Rejuran



How Korean Clinics Choose a Rejuran Alternative

In Korea, treatment selection is usually based on:

• Skin thickness and sensitivity
• Primary concern (repair vs hydration vs firmness)
• Desired downtime
• Long-term vs short-term results
• Combination treatment planning

Rather than replacing Rejuran directly, clinics often combine skin boosters with lasers, RF, or HIFU to achieve more balanced and longer-lasting results.